Aerpio(美国)

Aerpio Therapeutics

美国Aerpio www.aerpio.comAerpioTherapeutics公司宣布其作为一个独立的临床阶段生物技术公司而开张，开发治疗多种疾病的新型小分子Tie-2激动剂和HIF-1a稳定剂。Aerpio公司是从AkebiaTherapeutics公司中剥离出来的AerpioTherapeuticsisanew,clinical-stagebiotechnologycompanyfocus edonthedevelopmentofnovelsmallmoleculesandmonoclonalantibodiesforthetreatmentofvasculardiseaseandenhancementofwoundhealing.Aerpiowascreatedinaspin-outtransactionfromAkebiaTherapeuticstoenablemorerapiddevelopmentofitsexcitingcompounds.ItismanagedbythesamesuccessfulteamfromAkebia,employingasimilaroutsourcedapproachtopharmaceuticaldevelopment.Aerpio'stwoleadprogramsincludeaTie-2activatorfordiabeticmacularedema(DME)andvascularleak,andaHypoxia-inducibleFactor1-α(HIF1-α)stabilizerforwoundhealingandthetreatmentofinflammatoryboweldisease.TheleadcompoundfortheTie-2program,AKB-9778,iscurrentlycompletingitsinitialPhase1clini