Sangamo(美国)

Sangamo BioSciences

美国SangamoBioScienceswww.sangamo.comSangamoBioSciences,公司(Nasdaq:SGMO)是锌指核酸酶研究领域的先锋。SigmaLifeScience是其合作伙伴，因而是已获验证的含ZFN技术研究试剂的来源 Sangamoisaclinicalstagebiopharmaceuticalcompanyfocusedontheresearch,deve lopmentandcommercializationofengineeredDNA-bindingproteinsforthedevelopmentofnoveltherapeuticstrategiesforunmetmedicalneeds.Weareworldwideleadersinthedevelopmentofaproprietarytechnologyplatformthatenablesspecificregulationofgeneexpressionandgenemodification.Thebasisofthisplatformisanaturallyoccurringclassoftranscriptionfactors,zincfingerDNA-bindingproteins(ZFPs)whichwecanengineertodrivedesiredtherapeuticoutcomes.EngineeredZFPscanbelinkedtofunctionaldomainsthatnormallyactivateorrepressgeneexpressiontocreateZFPtranscriptionfactors(ZFPTFs)capableofturninggenesonoroff.WecanalsolinkZFPstonucleasedomainstocreatezincfingernucle