MicroSource Discovery(美国)

MicroSource Discovery Systems

MicroSourceDiscoverySystemswww.msdiscovery.com作为化合物微孔板格式的先行者，Microsource公司自1993年建立伊始，一直从事于天然产物和药物活性化合物的研发和生产。Compoundtestresourceshasalwaysbeenabottleneckinthedevelopmentofscreeningprogramsinthepharma ceuticalandagrochemicalindustries.Priorto1993itwascustomaryforcompanies,bigandsmall,torelyontheirarchivallibrariesandthepurchaseofcompoundsamplesfromvendorsthatservedasmiddlemenintheaccumulationofdiversesyntheticcompoundsfromamyriadofsourcesworldwide.Problemsarose,however,whena"start-up"discoverycompanyattemptedtoestablishausefullibraryof10,000to50,000compoundsasacorescreeningresource.Withminimumsamplepurchases(~50milligrams)at$50percompound,suchcompaniessoondiscoveredthatasignificantamountoftheirstart-upcapitalwasconsumedinaccessingthiscriticalresource.In1993,MicroSourceDiscoverySystems,Inc.(MDSI)pioneeredtheprovisiono