KaloBios(美国)

KaloBios Pharmaceuticals

美国KaloBiosPharmaceuticalswww.kalobios.comHumaneering（TM）是KaloBios制药的专利治疗方法，用于将非人体抗体转为应用于治疗药物的工程人体抗体。该系统具有保持抗原决定基特异性和提高亲和性的优点。KaloBios正在有限的基础上提供利用humaneering（TM）功能的机会。KaloBiosPharmaceuticals,Inc.,aU.S. based,privatemonoclonalcompany,usesitsbiologiccapabilitiesanditsproprietaryplatformtechnologytodevelopfirst-in-classhumanantibodytherapeutics.ThecompanyhasmultipleprogramsthatwereinsevenPhase1or2clinicaltrialsin2008/09:KB001isananti-infectiveforPseudomonasaeruginosainfectionsbeingtestedincysticfibrosisandinintensivecarepatientsonaventilator,andKB002andKB003arebeingevaluatedininflammatoryconditions,suchasrheumatoidarthritisandasthma.KB004isinpreclinicaldevelopmentforoncology,andthecompanyplanstofileanINDforitin1H2010.Thecompany抯Humaneering?technologyoffersadvantagesoverothermethodsofhumanantibodycreationintermsofimmunogenicity,potency,andmanufactur