SAGE Therapeutics(美国)

SAGE Therapeutics

SAGETherapeuticswww.sagerx.com开发治疗中枢神经系统（CNS）疾病药物SAGETherapeuticsisaneuroscience-focusedcompanydevelopingtherapiestotreatCNSspecialtyandorphandiseases.Thecompanyhasidentifiedseveralproductopportunitie swithclearandacceleratedpathstoregulatoryapproval.SAGE’sinitialpipelineincludesprogramsinstatusepilepticus,anesthesia,FragileXSyndromeandtraumaticbraininjury,whereCNSdrugspoorlyaddresstheareasofmosturgentpatientneedandareoftenaccompaniedbyconsiderablesideeffects.Thecompany’srobustallostericmodulatorchemistryplatform–calledthePositiveandNegativeAllostericModulator(PANAM)platform–hasgeneratedmultiplenewchemicalentitiessupportedbypromisingpreclinicaldatawiththepotentialtoleadtoproductswithmultipleindicationsoverthenextseveralyears.SAGETherapeuticsisaprivatecompanylaunchedin2011byaproventeamofR&Dleaders,renowned